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Cochrane review: Pregabalin for neuropathic pain

4th March 2019

A review update, for an earlier Cochrane review in 2009, for the use of pregabalin for neuropathic pain in adults has not shown an substantial change from the original findings. The authors’ concluded:

“Evidence shows efficacy of pregabalin in postherpetic neuralgia, painful diabetic neuralgia, and mixed or unclassified post-traumatic neuropathic pain, and absence of efficacy in HIV neuropathy; evidence of efficacy in central neuropathic pain is inadequate. Some people will derive substantial benefit with pregabalin; more will have moderate benefit, but many will have no benefit or will discontinue treatment.”

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